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c6 rat glioma  (ATCC)


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    Structured Review

    ATCC c6 rat glioma
    Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits on cell viability A – C and cell proliferation D – F in <t>C6</t> rat glioma cells at 72 h A and D , 48 h B and E , and 24 h C and F . Data are expressed as mean ± standard error and analyzed by one-way ANOVA with Tukey’s post-hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate
    C6 Rat Glioma, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1968 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rat+c6+glioma/C6/pmc13649818-52-4-21
    Average 96 stars, based on 1968 article reviews
    c6 rat glioma - by Bioz Stars, 2026-10
    96/100 stars

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    1) Product Images from "Characterization and Selective Antiglioma Activity of a Standardized Hydroalcoholic Extract from Yellow Psidium cattleianum Fruits"

    Article Title: Characterization and Selective Antiglioma Activity of a Standardized Hydroalcoholic Extract from Yellow Psidium cattleianum Fruits

    Journal: Neurochemical Research

    doi: 10.1007/s11064-026-04907-3

    Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits on cell viability A – C and cell proliferation D – F in C6 rat glioma cells at 72 h A and D , 48 h B and E , and 24 h C and F . Data are expressed as mean ± standard error and analyzed by one-way ANOVA with Tukey’s post-hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate
    Figure Legend Snippet: Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits on cell viability A – C and cell proliferation D – F in C6 rat glioma cells at 72 h A and D , 48 h B and E , and 24 h C and F . Data are expressed as mean ± standard error and analyzed by one-way ANOVA with Tukey’s post-hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Techniques Used: Control

    Clonogenic assay of C6 rat glioma cells: untreated A and treated with hydroalcoholic extract from yellow Psidium cattleianum fruits (1500 µg/mL) for 48 h B . Graphic representation of colony number C and colony size D . Data are expressed as mean ± standard error and analyzed by Student’s t-test. * p < 0.05 significantly different from the control. Three independent experiments were performed in triplicate
    Figure Legend Snippet: Clonogenic assay of C6 rat glioma cells: untreated A and treated with hydroalcoholic extract from yellow Psidium cattleianum fruits (1500 µg/mL) for 48 h B . Graphic representation of colony number C and colony size D . Data are expressed as mean ± standard error and analyzed by Student’s t-test. * p < 0.05 significantly different from the control. Three independent experiments were performed in triplicate

    Techniques Used: Clonogenic Assay, Control

    Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (750 µg/mL) on the migration of C6 rat glioma cells at 0, 2, 4, 6, and 24 h A and B . Data are expressed as mean ± standard error and analyzed by two-way ANOVA with Bonferroni’s post-hoc test. ** p ˂ 0.01, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate
    Figure Legend Snippet: Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (750 µg/mL) on the migration of C6 rat glioma cells at 0, 2, 4, 6, and 24 h A and B . Data are expressed as mean ± standard error and analyzed by two-way ANOVA with Bonferroni’s post-hoc test. ** p ˂ 0.01, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Techniques Used: Migration, Control

    Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (750–2000 µg/mL) on cell death in C6 rat glioma cell line at 72 h. Data are expressed as mean ± standard error and analyzed by two-way ANOVA with Tukey’s post-hoc test. ** p ˂ 0.01, *** p ˂ 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate
    Figure Legend Snippet: Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (750–2000 µg/mL) on cell death in C6 rat glioma cell line at 72 h. Data are expressed as mean ± standard error and analyzed by two-way ANOVA with Tukey’s post-hoc test. ** p ˂ 0.01, *** p ˂ 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Techniques Used: Control

    Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (500–2000 µg/mL) on redox equilibrium parameters in C6 rat glioma cell line after 48 h. A Reactive oxygen species levels (ROS); B superoxide dismutase activity (SOD); C catalase activity (CAT); D glutathione peroxidase (GPx). Data are expressed as mean ± standard error and analyzed by one-way ANOVA with Tukey’s post-hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate
    Figure Legend Snippet: Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (500–2000 µg/mL) on redox equilibrium parameters in C6 rat glioma cell line after 48 h. A Reactive oxygen species levels (ROS); B superoxide dismutase activity (SOD); C catalase activity (CAT); D glutathione peroxidase (GPx). Data are expressed as mean ± standard error and analyzed by one-way ANOVA with Tukey’s post-hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Techniques Used: Activity Assay, Control

    Related Articles

    Cell Culture:

    Article Title: ErCas12a CRISPR-MAD7 for Model Generation in Human Cells, Mice, and Rats.
    Article Snippet: .. Mouse Neuro-2A (cat. # CCL-131; ATCC) and rat C6 glioma (cat. # CCL-107; ATCC) cells were cultured and nucleofected as previously reported with CRISPR-Cas9 reagents.15 Briefly, cells were nucleofected with 2 lg each MAD7 mRNA and gRNA, cultured for 48 h, and then screened for MAD7 cutting activity. ..

    Article Title: ErCas12a CRISPR-MAD7 for Model Generation in Human Cells, Mice, and Rats
    Article Snippet: .. Mouse Neuro-2A (cat. # CCL-131; ATCC) and rat C6 glioma (cat. # CCL-107; ATCC) cells were cultured and nucleofected as previously reported with CRISPR-Cas9 reagents. ..

    Article Title: Efficacy and mechanism of poloxamine-assisted polyplex transfection
    Article Snippet: .. Rat C6 glioma (C6, ATCC, Manassas, VA) were cultured in Dulbecco’s Modification of Eagle’s Medium/Ham’s F-12 50/50 mix with L-glutamine (DMEM/F12, Mediatech, Manassas, VA) with 5% bovine growth serum (BGS) (Hyclone, Logan, UT) and 1% penicillin and streptomycin (Mediatech). .. Normal human dermal fibroblasts (NHDF, Lonza, Walkersville, MD) were cultured in DMEM/F12 with 10% BGS and 1% penicillin and streptomycin.

    CRISPR:

    Article Title: ErCas12a CRISPR-MAD7 for Model Generation in Human Cells, Mice, and Rats.
    Article Snippet: .. Mouse Neuro-2A (cat. # CCL-131; ATCC) and rat C6 glioma (cat. # CCL-107; ATCC) cells were cultured and nucleofected as previously reported with CRISPR-Cas9 reagents.15 Briefly, cells were nucleofected with 2 lg each MAD7 mRNA and gRNA, cultured for 48 h, and then screened for MAD7 cutting activity. ..

    Article Title: ErCas12a CRISPR-MAD7 for Model Generation in Human Cells, Mice, and Rats
    Article Snippet: .. Mouse Neuro-2A (cat. # CCL-131; ATCC) and rat C6 glioma (cat. # CCL-107; ATCC) cells were cultured and nucleofected as previously reported with CRISPR-Cas9 reagents. ..

    Activity Assay:

    Article Title: ErCas12a CRISPR-MAD7 for Model Generation in Human Cells, Mice, and Rats.
    Article Snippet: .. Mouse Neuro-2A (cat. # CCL-131; ATCC) and rat C6 glioma (cat. # CCL-107; ATCC) cells were cultured and nucleofected as previously reported with CRISPR-Cas9 reagents.15 Briefly, cells were nucleofected with 2 lg each MAD7 mRNA and gRNA, cultured for 48 h, and then screened for MAD7 cutting activity. ..

    Modification:

    Article Title: Efficacy and mechanism of poloxamine-assisted polyplex transfection
    Article Snippet: .. Rat C6 glioma (C6, ATCC, Manassas, VA) were cultured in Dulbecco’s Modification of Eagle’s Medium/Ham’s F-12 50/50 mix with L-glutamine (DMEM/F12, Mediatech, Manassas, VA) with 5% bovine growth serum (BGS) (Hyclone, Logan, UT) and 1% penicillin and streptomycin (Mediatech). .. Normal human dermal fibroblasts (NHDF, Lonza, Walkersville, MD) were cultured in DMEM/F12 with 10% BGS and 1% penicillin and streptomycin.



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    qRT-PCR analysis of ferroptosis-related gene expression after sevoflurane and H 2 O 2 exposure. Relative expression of GPX4, SLC7A11, ACSL4, and PTGS2 in Control, Sevo (3.3% for 6 h), H 2 O 2 (200 μM for 24 h), and Sevo + H 2 O 2 groups in <t>C6</t> glioma cells and HA astrocytes. *P < 0.05 versus Control; significant comparisons are displayed with a single asterisk. Data represent mean ± SEM from three independent experiments. Two-way ANOVA (sevoflurane × H 2 O 2 ) was followed by Dunnett’s multiple-comparisons test against Control.
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    Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits on cell viability A – C and cell proliferation D – F in C6 rat glioma cells at 72 h A and D , 48 h B and E , and 24 h C and F . Data are expressed as mean ± standard error and analyzed by one-way ANOVA with Tukey’s post-hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Journal: Neurochemical Research

    Article Title: Characterization and Selective Antiglioma Activity of a Standardized Hydroalcoholic Extract from Yellow Psidium cattleianum Fruits

    doi: 10.1007/s11064-026-04907-3

    Figure Lengend Snippet: Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits on cell viability A – C and cell proliferation D – F in C6 rat glioma cells at 72 h A and D , 48 h B and E , and 24 h C and F . Data are expressed as mean ± standard error and analyzed by one-way ANOVA with Tukey’s post-hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Article Snippet: Cell lines used were C6 (rat glioma), U87MG (human glioma), L929 (mouse fibroblast), and MRC5 (human fibroblast), all purchased from the American Type Culture Collection (ATCC, USA).

    Techniques: Control

    Clonogenic assay of C6 rat glioma cells: untreated A and treated with hydroalcoholic extract from yellow Psidium cattleianum fruits (1500 µg/mL) for 48 h B . Graphic representation of colony number C and colony size D . Data are expressed as mean ± standard error and analyzed by Student’s t-test. * p < 0.05 significantly different from the control. Three independent experiments were performed in triplicate

    Journal: Neurochemical Research

    Article Title: Characterization and Selective Antiglioma Activity of a Standardized Hydroalcoholic Extract from Yellow Psidium cattleianum Fruits

    doi: 10.1007/s11064-026-04907-3

    Figure Lengend Snippet: Clonogenic assay of C6 rat glioma cells: untreated A and treated with hydroalcoholic extract from yellow Psidium cattleianum fruits (1500 µg/mL) for 48 h B . Graphic representation of colony number C and colony size D . Data are expressed as mean ± standard error and analyzed by Student’s t-test. * p < 0.05 significantly different from the control. Three independent experiments were performed in triplicate

    Article Snippet: Cell lines used were C6 (rat glioma), U87MG (human glioma), L929 (mouse fibroblast), and MRC5 (human fibroblast), all purchased from the American Type Culture Collection (ATCC, USA).

    Techniques: Clonogenic Assay, Control

    Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (750 µg/mL) on the migration of C6 rat glioma cells at 0, 2, 4, 6, and 24 h A and B . Data are expressed as mean ± standard error and analyzed by two-way ANOVA with Bonferroni’s post-hoc test. ** p ˂ 0.01, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Journal: Neurochemical Research

    Article Title: Characterization and Selective Antiglioma Activity of a Standardized Hydroalcoholic Extract from Yellow Psidium cattleianum Fruits

    doi: 10.1007/s11064-026-04907-3

    Figure Lengend Snippet: Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (750 µg/mL) on the migration of C6 rat glioma cells at 0, 2, 4, 6, and 24 h A and B . Data are expressed as mean ± standard error and analyzed by two-way ANOVA with Bonferroni’s post-hoc test. ** p ˂ 0.01, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Article Snippet: Cell lines used were C6 (rat glioma), U87MG (human glioma), L929 (mouse fibroblast), and MRC5 (human fibroblast), all purchased from the American Type Culture Collection (ATCC, USA).

    Techniques: Migration, Control

    Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (750–2000 µg/mL) on cell death in C6 rat glioma cell line at 72 h. Data are expressed as mean ± standard error and analyzed by two-way ANOVA with Tukey’s post-hoc test. ** p ˂ 0.01, *** p ˂ 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Journal: Neurochemical Research

    Article Title: Characterization and Selective Antiglioma Activity of a Standardized Hydroalcoholic Extract from Yellow Psidium cattleianum Fruits

    doi: 10.1007/s11064-026-04907-3

    Figure Lengend Snippet: Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (750–2000 µg/mL) on cell death in C6 rat glioma cell line at 72 h. Data are expressed as mean ± standard error and analyzed by two-way ANOVA with Tukey’s post-hoc test. ** p ˂ 0.01, *** p ˂ 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Article Snippet: Cell lines used were C6 (rat glioma), U87MG (human glioma), L929 (mouse fibroblast), and MRC5 (human fibroblast), all purchased from the American Type Culture Collection (ATCC, USA).

    Techniques: Control

    Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (500–2000 µg/mL) on redox equilibrium parameters in C6 rat glioma cell line after 48 h. A Reactive oxygen species levels (ROS); B superoxide dismutase activity (SOD); C catalase activity (CAT); D glutathione peroxidase (GPx). Data are expressed as mean ± standard error and analyzed by one-way ANOVA with Tukey’s post-hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Journal: Neurochemical Research

    Article Title: Characterization and Selective Antiglioma Activity of a Standardized Hydroalcoholic Extract from Yellow Psidium cattleianum Fruits

    doi: 10.1007/s11064-026-04907-3

    Figure Lengend Snippet: Effect of hydroalcoholic extract from yellow Psidium cattleianum fruits (500–2000 µg/mL) on redox equilibrium parameters in C6 rat glioma cell line after 48 h. A Reactive oxygen species levels (ROS); B superoxide dismutase activity (SOD); C catalase activity (CAT); D glutathione peroxidase (GPx). Data are expressed as mean ± standard error and analyzed by one-way ANOVA with Tukey’s post-hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 significantly different from the control. Three independent experiments were performed in triplicate

    Article Snippet: Cell lines used were C6 (rat glioma), U87MG (human glioma), L929 (mouse fibroblast), and MRC5 (human fibroblast), all purchased from the American Type Culture Collection (ATCC, USA).

    Techniques: Activity Assay, Control

    qRT-PCR analysis of ferroptosis-related gene expression after sevoflurane and H 2 O 2 exposure. Relative expression of GPX4, SLC7A11, ACSL4, and PTGS2 in Control, Sevo (3.3% for 6 h), H 2 O 2 (200 μM for 24 h), and Sevo + H 2 O 2 groups in C6 glioma cells and HA astrocytes. *P < 0.05 versus Control; significant comparisons are displayed with a single asterisk. Data represent mean ± SEM from three independent experiments. Two-way ANOVA (sevoflurane × H 2 O 2 ) was followed by Dunnett’s multiple-comparisons test against Control.

    Journal: Frontiers in Cell and Developmental Biology

    Article Title: Integrated re-analysis of bulk and single-cell transcriptomic data reveals limited ferroptosis and neuroinflammation signatures after sevoflurane exposure in the aged rat hippocampus and human prefrontal cortex cells

    doi: 10.3389/fcell.2026.1938601

    Figure Lengend Snippet: qRT-PCR analysis of ferroptosis-related gene expression after sevoflurane and H 2 O 2 exposure. Relative expression of GPX4, SLC7A11, ACSL4, and PTGS2 in Control, Sevo (3.3% for 6 h), H 2 O 2 (200 μM for 24 h), and Sevo + H 2 O 2 groups in C6 glioma cells and HA astrocytes. *P < 0.05 versus Control; significant comparisons are displayed with a single asterisk. Data represent mean ± SEM from three independent experiments. Two-way ANOVA (sevoflurane × H 2 O 2 ) was followed by Dunnett’s multiple-comparisons test against Control.

    Article Snippet: To examine regulation of key ferroptosis-related genes identified in the transcriptomic analyses, quantitative RT-PCR was performed in C6 rat glioma cells (ATCC CRL-2309) and HA human astrocytes (ATCC CRL-3050).

    Techniques: Quantitative RT-PCR, Analysis, Gene Expression, Expressing, Control